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What is Vagostin

Vagostin affects chemicals in the body that are involved in the communication between nerve impulses and muscle movement.
Vagostin is used to treat the symptoms of myasthenia gravis.
Vagostin may also be used for purposes not listed in Vagostin guide.

Vagostin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Vagostin and call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Vagostin dosing

Usual Adult Dose for Reversal of Neuromuscular Blockade:

Initial dose: 0.03 mg/kg to 0.07 mg/kg injected intravenously over a period of at least 1 minute
Maximum dose: 0.07 mg/kg or up to a total of 5 mg, whichever is less
Comments:
-Administer an anticholinergic agent intravenously prior to or concomitantly with Vagostin using a separate syringe. In the presence of bradycardia, administer the anticholinergic prior to Vagostin
-Administered by trained healthcare providers familiar with neuromuscular blocking and reversal agents
-Use a peripheral nerve stimulator to determine initiation time and need for additional doses

Usual Adult Dose for Myasthenia Gravis:

Oral:
15 to 375 mg orally daily
Average dose: 150 mg orally over a 24 hour period
Comments:
-Therapy is required day and night with the larger portion of the total daily dose given at times when the patient is more prone to fatigue
-Dosage schedule should be individualized for each patient
Parenteral:
1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly

Usual Adult Dose for Urinary Retention:

Prevention of Postoperative Distention:
Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation
Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days.
Treatment of Postoperative Distention: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly
Prevention of Urinary Retention:
Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation
Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days
Treatment of Urinary Retention:
Initial: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly
Duration of therapy: After patient has voided continue 0.5 mg subcutaneously or intramuscularly every 3 hours for at least 5 injections.
Comments:
-If urination does not occur in an hour consider catherization

Usual Pediatric Dose for Reversal of Neuromuscular Blockade:

Initial dose: 0.03 mg/kg to 0.07 mg/kg injected intravenously over a period of at least 1 minute
Maximum dose: 0.07 mg/kg or up to a total of 5 mg, whichever is less
Comments:
-Administer an anticholinergic agent intravenously prior to or concomitantly with Vagostin using a separate syringe. In the presence of bradycardia, administer the anticholinergic prior to Vagostin
-Administered by trained healthcare providers familiar with neuromuscular blocking and reversal agents
-Use a peripheral nerve stimulator to determine initiation time and need for additional doses

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
2 .5mg/1ml5 ml$1.26
MYOSTIGMIN 0.5MG/ML INJECTION 1ML 1 vial(s) (10 injections each) $0.62Neon Laboratories Ltd
2 .5 mg x 5 mL x 4's $1.21
0 .5mg/1ml1 ml$0.06
Neostigmine Methyl Sulphate 0.5 mg Injection $0.06
15 mg10 Tablet$0.51
15 mg100 $65.07Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
15 mg100 $77.45Australia, Canada, NZ, Singapore, Turkey, UK, USA
15 mg100 $87.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
PROSTIGMIN inj 0.5 mg x 1 mL x 1ml $0.05AHPL
PROSTIGMIN tab 15 mg x 10's $0.51AHPL
0 .5mg1 vial$0.12
12 .5mg1 vial$0.32
12 .5 mg x 5's $1.57
Stimin 12.5mg AMP / 5 $1.57
STIMIN inj 12.5 mg x 1ml $0.32Celon (Revilon)
Stimin 12.5 mg Injection $0.32
STIMIN inj 0.5 mg x 1ml $0.12Celon (Revilon)
Stimin 0.5 mg Injection $0.12
0 .5 mg x 10's $1.20
Stimin 0.5mg AMP / 10 $1.20
TILSTIGMIN inj 0.5 mg x 1 mL x 5ml $0.19Tablets
Tilstigmin 0.5 mg Injection $0.07
Tilstigmin 15mg TAB / 10 $0.93
TILSTIGMIN tab 15 mg x 10's $1.24Tablets
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References

  1. "Neostigmine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  2. "Neostigmine". http://www.drugbank.ca/drugs/DB0140... (accessed August 28, 2018).
  3. "3982twq96g: the unique ingredient identifier (unii) is an alphanumeric substance identifier from the joint fda/usp substance registration system (srs).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Vagostin - Frequently asked Questions

Can Vagostin be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Vagostin?

You should not use this medication if you are allergic to Vagostin or pyridostigmine (Mestinon), or if you have a bladder or bowel obstruction, or a serious stomach disorder called peritonitis.

To make sure you can safely take Vagostin, tell your doctor if you have any of these other conditions:

FDA pregnancy category C. It is not known whether Vagostin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. You should not take Vagostin during late pregnancy.

It is not known whether Vagostin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Vagostin.

What other drugs will affect Vagostin?

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Vagostin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

How should I take Vagostin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with food or milk if it upsets your stomach.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor's instructions about how much medicine to take and when to take it. You may need to take Vagostin at evenly spaced intervals around the clock.

Your doctor may occasionally change your dose to make sure you get the best results. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need surgery, tell the surgeon ahead of time that you are using Vagostin. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture, heat, and light.

Can Vagostin be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Vagostin be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Vagostin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Vagostin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology