It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Tilstigmin before taking it.
What is Tilstigmin
Tilstigmin affects chemicals in the body that are involved in the communication between nerve impulses and muscle movement. Tilstigmin is used to treat the symptoms of myasthenia gravis. Tilstigmin may also be used for purposes not listed in Tilstigmin guide.
Tilstigmin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Tilstigmin and call your doctor at once if you have any of these serious side effects:
extreme muscle weakness;
slurred speech, vision problems;
feeling like you might pass out;
severe stomach cramps or diarrhea;
trouble breathing, cough with mucus;
fast or slow heart rate;
seizure ; or
worsening or no improvement in your symptoms of myasthenia gravis.
Less serious side effects may include:
headache, drowsiness;
mild nausea, vomiting, gas;
urinating more than usual;
cold sweat, warmth or tingly feeling; or
mild rash or itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail)
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Tilstigmin dosing
Usual Adult Dose for Reversal of Neuromuscular Blockade:
Initial dose: 0.03 mg/kg to 0.07 mg/kg injected intravenously over a period of at least 1 minute Maximum dose: 0.07 mg/kg or up to a total of 5 mg, whichever is less Comments: -Administer an anticholinergic agent intravenously prior to or concomitantly with Tilstigmin using a separate syringe. In the presence of bradycardia, administer the anticholinergic prior to Tilstigmin -Administered by trained healthcare providers familiar with neuromuscular blocking and reversal agents -Use a peripheral nerve stimulator to determine initiation time and need for additional doses
Usual Adult Dose for Myasthenia Gravis:
Oral: 15 to 375 mg orally daily Average dose: 150 mg orally over a 24 hour period Comments: -Therapy is required day and night with the larger portion of the total daily dose given at times when the patient is more prone to fatigue -Dosage schedule should be individualized for each patient Parenteral: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly
Usual Adult Dose for Urinary Retention:
Prevention of Postoperative Distention: Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days. Treatment of Postoperative Distention: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly Prevention of Urinary Retention: Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days Treatment of Urinary Retention: Initial: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly Duration of therapy: After patient has voided continue 0.5 mg subcutaneously or intramuscularly every 3 hours for at least 5 injections. Comments: -If urination does not occur in an hour consider catherization
Usual Pediatric Dose for Reversal of Neuromuscular Blockade:
Initial dose: 0.03 mg/kg to 0.07 mg/kg injected intravenously over a period of at least 1 minute Maximum dose: 0.07 mg/kg or up to a total of 5 mg, whichever is less Comments: -Administer an anticholinergic agent intravenously prior to or concomitantly with Tilstigmin using a separate syringe. In the presence of bradycardia, administer the anticholinergic prior to Tilstigmin -Administered by trained healthcare providers familiar with neuromuscular blocking and reversal agents -Use a peripheral nerve stimulator to determine initiation time and need for additional doses
Prices of the drug can vary in different shops. There will be a variation in price from pharmacy to an online shop. Most online shops will have a little lower price when compared to pharmacy stores, so you need to cross check before buying. Just go to a nearest pharmacy store and check for prices before you decide on buying. You should also be checking and comparing prices among various online stores and should be choosing the affordable and best store. The prices also vary based on brands, and you should note few stores sell specific brands, and you should learn to compare prices of same brand in different stores. Below are the prices of Tilstigmin medicine in some well-known online stores.
Strength
Quantity
Price, USD
Country
Tablets (India) Limited
15 mg
10 Tablet
$0.82
India
Select the most affordable brand or generic drug
Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.
"3982twq96g: the unique ingredient identifier (unii) is an alphanumeric substance identifier from the joint fda/usp substance registration system (srs).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).
Tilstigmin - Frequently asked Questions
Can Tilstigmin be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
How should I take Tilstigmin?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Take this medicine with food or milk if it upsets your stomach.
Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.
The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor's instructions about how much medicine to take and when to take it. You may need to take Tilstigmin at evenly spaced intervals around the clock.
Your doctor may occasionally change your dose to make sure you get the best results. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.
If you need surgery, tell the surgeon ahead of time that you are using Tilstigmin. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture, heat, and light.
What other drugs will affect Tilstigmin?
Tell your doctor about all other medicines you use, especially:
an antibiotic such as neomycin (Mycifradin, Neo Fradin, Neo Tab), kanamycin (Kantrex), or streptomycin, tobramycin (Nebcin, Tobi);
bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);
cold medicine, allergy medicine, or sleeping pills that contain an antihistamine such as diphenhydramine (Tylenol PM) or doxylamine (Unisom);
heart rhythm medication such as quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);
medicine to treat Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or
a steroid such as betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).
This list is not complete and other drugs may interact with Tilstigmin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Who should not take Tilstigmin?
You should not use this medication if you are allergic to Tilstigmin or pyridostigmine (Mestinon), or if you have a bladder or bowel obstruction, or a serious stomach disorder called peritonitis.
To make sure you can safely take Tilstigmin, tell your doctor if you have any of these other conditions:
asthma;
kidney disease;
slow heartbeats or other heart rhythm disorder;
high blood pressure, heart disease, coronary artery disease;
an ulcer or other serious stomach disorder;
overactive thyroid; or
a history of seizures.
FDA pregnancy category C. It is not known whether Tilstigmin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. You should not take Tilstigmin during late pregnancy.
It is not known whether Tilstigmin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Tilstigmin.
Can Tilstigmin be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Tilstigmin be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Tilstigmin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Tilstigmin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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