Neostigmine Injection BP

Name: Neostigmine Injection BP Price Comparison: Uses, Dosage, Form & Side Effects
Creator: gmedication.com
Published: 2021-11-01T10:10:10+00:00

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What is Neostigmine Injection BP
Neostigmine Injection BP side effects
Neostigmine Injection BP dosing

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Frequently asked Questions

Who should not take Neostigmine Injection BP?
How should I take Neostigmine Injection BP?
What other drugs will affect Neostigmine Injection BP?

Neostigmine Injection BP reviews

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What is Neostigmine Injection BP

Neostigmine Injection BP affects chemicals in the body that are involved in the communication between nerve impulses and muscle movement.
Neostigmine Injection BP is used to treat the symptoms of myasthenia gravis.
Neostigmine Injection BP may also be used for purposes not listed in Neostigmine Injection BP guide.

Neostigmine Injection BP side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Neostigmine Injection BP and call your doctor at once if you have any of these serious side effects:

extreme muscle weakness;
slurred speech, vision problems;
feeling like you might pass out;
severe stomach cramps or diarrhea;
trouble breathing, cough with mucus;
fast or slow heart rate;
seizure ; or
worsening or no improvement in your symptoms of myasthenia gravis.

Less serious side effects may include:

headache, drowsiness;
mild nausea, vomiting, gas;
urinating more than usual;
cold sweat, warmth or tingly feeling; or
mild rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Neostigmine Injection BP dosing

Usual Adult Dose for Reversal of Neuromuscular Blockade:

Initial dose: 0.03 mg/kg to 0.07 mg/kg injected intravenously over a period of at least 1 minute
Maximum dose: 0.07 mg/kg or up to a total of 5 mg, whichever is less
Comments:
-Administer an anticholinergic agent intravenously prior to or concomitantly with Neostigmine Injection BP using a separate syringe. In the presence of bradycardia, administer the anticholinergic prior to Neostigmine Injection BP
-Administered by trained healthcare providers familiar with neuromuscular blocking and reversal agents
-Use a peripheral nerve stimulator to determine initiation time and need for additional doses

Usual Adult Dose for Myasthenia Gravis:

Oral:
15 to 375 mg orally daily
Average dose: 150 mg orally over a 24 hour period
Comments:
-Therapy is required day and night with the larger portion of the total daily dose given at times when the patient is more prone to fatigue
-Dosage schedule should be individualized for each patient
Parenteral:
1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly

Usual Adult Dose for Urinary Retention:

Prevention of Postoperative Distention:
Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation
Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days.
Treatment of Postoperative Distention: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly
Prevention of Urinary Retention:
Initial dose: 0.25 mg subcutaneously or intramuscularly as soon as possible after operation
Duration of therapy: Repeat every 4 to 6 hours for 2 to 3 days
Treatment of Urinary Retention:
Initial: 1 mL of 1:2000 solution (0.5 mg) subcutaneously or intramuscularly
Duration of therapy: After patient has voided continue 0.5 mg subcutaneously or intramuscularly every 3 hours for at least 5 injections.
Comments:
-If urination does not occur in an hour consider catherization

Usual Pediatric Dose for Reversal of Neuromuscular Blockade:

Active ingredients: Neostigmine

Select the most affordable brand or generic drug

Strength	Quantity	Price, USD	Country
Amostigmine
Endure Medical Neostigmine
Epistigmin
Eyesmin
Konstigmin
Miostin
Myostigmin (5ml)
0 .5mg/1ml	1 ml	$1.12
Myostigmin 2.5mg Injection		$0.06	Neon Laboratories Ltd
Myostigmin 0.5mg/mL INJ / 10x1ml		$1.07
Neostigmin SAD
Neostigmina
Neostigmina Braun
Neostigmina Metilsulfato Biosano
Neostigmina Metilsulfato Sanderson
Neostigmina Norgreen
Neostigmina Northia
Neostigmine Amriya
Neostigmine Methyl Sulphate
0 .5mg/1ml	1 ml	$0.06
Neostigmine Methyl Sulphate 0.5 mg Injection		$0.06
Neostigmine Methylsulphate
Neostigmine Methylsulphate Injection
Neostigmine Methylsulphate P & D
Neostigmine Roche
Neostigmine Rotexmedica
Neostigmine-Bodene
Polstigminum
Prostigmin
15 mg	100	$65.99	Canada, Mauritius, Singapore, Turkey, UK, USA
15 mg	100	$72.00	Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
15 mg	100	$80.61	Barbados, Canada, NZ, UK
Prostigmin 0.5mg/mL INJ / 1ml		$0.05
PROSTIGMIN Capsule/ Tablet / 15mg (10 units)		$0.51	Nicholas Piramal
Stigmin
Stigmine
Stimin (12.5 mg)
0 .5mg	1 vial	$0.12
12 .5mg	1 vial	$0.32
12 .5 mg x 5's		$1.57
Stimin 12.5mg AMP / 5		$1.57
STIMIN inj 12.5 mg x 1ml		$0.32	Celon (Revilon)
Stimin 12.5 mg Injection		$0.32
STIMIN inj 0.5 mg x 1ml		$0.12	Celon (Revilon)
Stimin 0.5 mg Injection		$0.12
0 .5 mg x 10's		$1.20
Stimin 0.5mg AMP / 10		$1.20
Syntostigmin
Tilstigmin
15 mg	10 Tablet	$0.82
Tilstigmin 15mg Tablet		$0.06	Tablets India Limited
TILSTIGMIN Injection / 0.5mg (5x5ml units)		$0.93	Tablets (India)
Tilstigmin 15 mg Tablet		$0.10
Vagostin
Yi Ding

References

"Neostigmine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"Neostigmine". http://www.drugbank.ca/drugs/DB0140... (accessed August 28, 2018).
"3982twq96g: the unique ingredient identifier (unii) is an alphanumeric substance identifier from the joint fda/usp substance registration system (srs).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Neostigmine Injection BP - Frequently asked Questions

Can Neostigmine Injection BP be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Neostigmine Injection BP?

You should not use this medication if you are allergic to Neostigmine Injection BP or pyridostigmine (Mestinon), or if you have a bladder or bowel obstruction, or a serious stomach disorder called peritonitis.

To make sure you can safely take Neostigmine Injection BP, tell your doctor if you have any of these other conditions:

asthma;
kidney disease;
slow heartbeats or other heart rhythm disorder;
high blood pressure, heart disease, coronary artery disease;
an ulcer or other serious stomach disorder;
overactive thyroid; or
a history of seizures.

FDA pregnancy category C. It is not known whether Neostigmine Injection BP will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. You should not take Neostigmine Injection BP during late pregnancy.

It is not known whether Neostigmine Injection BP passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Neostigmine Injection BP.

How should I take Neostigmine Injection BP?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with food or milk if it upsets your stomach.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor's instructions about how much medicine to take and when to take it. You may need to take Neostigmine Injection BP at evenly spaced intervals around the clock.

Your doctor may occasionally change your dose to make sure you get the best results. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need surgery, tell the surgeon ahead of time that you are using Neostigmine Injection BP. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture, heat, and light.

What other drugs will affect Neostigmine Injection BP?

Tell your doctor about all other medicines you use, especially:

atropine (Atreza, Sal-Tropine);
belladonna (Donnatal, and others);
benztropine (Cogentin);
clidinium (Quarzan);
clozapine (Clozaril, FazaClo);
dimenhydrinate (Dramamine);
methscopolamine (Pamine), scopolamine (Transderm Scop);
glycopyrrolate (Robinul);
mepenzolate (Cantil);
an antibiotic such as neomycin (Mycifradin, Neo Fradin, Neo Tab), kanamycin (Kantrex), or streptomycin, tobramycin (Nebcin, Tobi);
bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);
cold medicine, allergy medicine, or sleeping pills that contain an antihistamine such as diphenhydramine (Tylenol PM) or doxylamine (Unisom);
heart rhythm medication such as quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);
medicine to treat Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or
a steroid such as betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list is not complete and other drugs may interact with Neostigmine Injection BP. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Can Neostigmine Injection BP be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Neostigmine Injection BP be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Neostigmine Injection BP, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Neostigmine Injection BP. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.