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Sinvastatina Germed |
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What is Sinvastatina Germed
Sinvastatina Germed is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Sinvastatina Germed reduces levels of "bad" cholesterol and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).Sinvastatina Germed is used to lower cholesterol and triglycerides (types of fat) in the blood.
Sinvastatina Germed is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Sinvastatina Germed is used in adults and children who are at least 10 years old.
Sinvastatina Germed may also be used for purposes not listed in Sinvastatina Germed guide.
Sinvastatina Germed side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.In rare cases, Sinvastatina Germed can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
- signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or
- liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice.
Common side effects may include:
- headache;
- constipation, nausea, stomach pain; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Sinvastatina Germed dosing
Usual Adult Dose for Prevention of Cardiovascular Disease:
Usual dosage range: 5 to 40 mg orally once a day in the eveningPatients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy, particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.
Usual Adult Dose for Cardiovascular Risk Reduction:
Usual dosage range: 5 to 40 mg orally once a day in the eveningPatients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy (including rhabdomyolysis), particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.
Usual Adult Dose for Homozygous Familial Hypercholesterolemia:
Recommended dose: 40 mg orally once a day in the eveningComments:
-Simvastatin should be used as an adjunct to other lipid-lowering treatments or alone if such treatments are unavailable.
Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:
Less than 10 years: Not recommended10 years or older:
Initial dose: 10 mg orally once a day in the evening
Maintenance dose: 10 to 40 mg orally once a day in the evening
Maximum dose: 40 mg orally once a day in the evening
Comments:
-Doses should be individualized according to the goal of therapy.
-Dose adjustments should be made at intervals of 4 weeks or more.
-Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment.
Approved indication:
-As an adjunct to diet to reduce total-C, LDL-C, and Apo B levels in adolescent boys and girls who are at least one year postmenarche, 10 to 17 years of age, with HeFH, if after an adequate trial of diet therapy the following findings are present:
1. LDL cholesterol remains 190 mg/dL or greater; or
2. LDL cholesterol remains 160 mg/dL or greater and there is a positive family history of premature cardiovascular disease (CVD) or two or more other CVD risk factors are present in the adolescent patient. The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C less than 130 mg/dL.
-The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.
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References
- Dailymed."Simvastatin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- "Simvastatin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "Simvastatin". http://www.drugbank.ca/drugs/DB0064... (accessed August 28, 2018).
Sinvastatina Germed - Frequently asked Questions
Can Sinvastatina Germed be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
How should I take Sinvastatina Germed?
Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.
Sinvastatina Germed is usually taken at bedtime or with an evening meal. If you take Sinvastatina Germed more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.
While using Sinvastatina Germed, you may need frequent blood tests at your doctor's office.
You may need to take Sinvastatina Germed on a long-term basis for the treatment of high cholesterol. You may need to stop using Sinvastatina Germed for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.
Sinvastatina Germed is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Store at room temperature away from moisture, heat, and light.
Who should not take Sinvastatina Germed?
You should not take Sinvastatina Germed if you are allergic to it, if you are pregnant or breast-feeding, or if you have active liver disease.
The following drugs can increase your risk of serious muscle problems if you take them together with Sinvastatina Germed. These drugs should not be used while you are taking Sinvastatina Germed:
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cyclosporine;
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danazol;
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gemfibrozil;
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nefazodone;
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an antibiotic--clarithromycin, erythromycin, telithromycin;
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antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
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hepatitis C medications--boceprevir, telaprevir; or
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HIV/AIDS medication--atazanavir, cobicistat, darunavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.
Before you start taking Sinvastatina Germed, tell your doctor if you are already using any of these other medicines:
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lomitapide; or
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heart medication--amiodarone, amlodipine, diltiazem, dronedarone, ranolazine, verapamil.
To make sure Sinvastatina Germed is safe for you, tell your doctor if you have:
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history of liver disease;
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history of kidney disease;
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diabetes;
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a thyroid disorder; or
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if you drink more than 2 alcoholic beverages daily.
Sinvastatina Germed can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take Sinvastatina Germed if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking Sinvastatina Germed.
Sinvastatina Germed may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Sinvastatina Germed.
What other drugs will affect Sinvastatina Germed?
Many drugs can interact with Sinvastatina Germed. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Sinvastatina Germed, especially:
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delavirdine;
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fenofibrate; or
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fluconazole.
This list is not complete and many other drugs can interact with Sinvastatina Germed. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Can Sinvastatina Germed be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Sinvastatina Germed be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
Reviews
Following the study conducted by gmedication.com on Sinvastatina Germed, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Sinvastatina Germed. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.Patient reports
Patient reported useful
No survey data has been collected yetPatient reported side effects
No survey data has been collected yetPatient reported price estimates
No survey data has been collected yetOne patient reported frequency of use
How often should I take Sinvastatina Germed?According to the survey, gmedication.com reported that users of Sinvastatina Germed should take Twice in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
| Patients | % | ||
|---|---|---|---|
| Twice in a day | 1 | 100.0% | |
Patient reported doses
No survey data has been collected yetPatient reported time for results
No survey data has been collected yetPatient reported administration
No survey data has been collected yetPatient reported age
No survey data has been collected yetPatient reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Vishal Pawar, MD Pharmacology