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Syntroxine |
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What is Syntroxine
Syntroxine is a replacement for a hormone normally produced by your thyroid gland to regulate the body's energy and metabolism. Syntroxine is given when the thyroid does not produce enough of this hormone on its own.Syntroxine treats hypothyroidism. Syntroxine is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.
Syntroxine may also be used for purposes not listed in Syntroxine guide.
Syntroxine side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have a serious side effect such as:
- fast or irregular heart rate;
- fever, hot flashes, sweating;
- sleep problems (insomnia);
- changes in your menstrual periods; or
- vomiting, diarrhea, appetite changes, weight changes.
Common side effects may include mild hair loss.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Syntroxine dosing
Usual Adult Dose for Hypothyroidism:
Oral:The initial dose is 12.5 to 50 mcg orally once a day. The dosage can be increased in 12.5 to 25 mcg/day increments every 2 to 4 weeks. In older patients or in younger patients with a history of cardiovascular disease, the dosage should be increased in 12.5 to 25 mcg increments every 3 to 6 weeks.
Few patients require doses higher than 200 mcg. Inadequate response to doses higher than 200 mcg is rare and may suggest malabsorption, poor patient compliance and/or drug interactions.
Parenteral: The usual IV or IM dose is 50 to 75% of the oral dose.
Usual Adult Dose for TSH Suppression:
Oral:The initial dose is 50 mcg orally once a day. The dosage may be increased in 25 to 50 mcg increments every 2 to 4 weeks. The typical maintenance dose is 100 to 200 mcg orally once a day.
Parenteral: The usual IV or IM dose is 50 to 75 % of the oral dose.
Usual Adult Dose for Thyroid Suppression Test:
Oral: 2.6 mcg/kg/day for 7 to 10 days.Parenteral: The usual IV or IM dose is 50 to 75% of the oral dose.
Usual Adult Dose for Myxedema Coma:
Initial dose: 300 to 500 mcg IV bolus administered one time.Maintenance dose: 75 to 100 mcg IV once a day until the patient can be converted to oral therapy.
Usual Pediatric Dose for Hypothyroidism:
Congenital hypothyroidism:Neonatal:
Oral: 10 to 15 mcg/kg/day; if patient is at risk for development of cardiac failure, begin with a lower dose. In severe cases of hypothyroidism, a higher initial dose of 12 to 17 mcg/kg/day may be considered.
IV or IM: 50% to 75% of the oral dose
Oral:
0 to 3 months: 10 to 15 mcg/kg orally once per day; if the infant is at risk for development of cardiac failure use a lower starting dose of approximately 25 mcg/day; if the initial serum T4 is very low (less than 5 mcg/dL) begin treatment at a higher dosage of approximately 50 mcg/day.
3 to 6 months: 8 to 10 mcg/kg or 25 to 50 mcg orally once per day
6 to 12 months: 6 to 8 mcg/kg or 50 to 75 mcg orally once per day
1 to 5 years: 5 to 6 mcg/kg or 75 to 100 mcg orally once per day
6 to 12 years: 4 to 5 mcg/kg or 100 to 125 mcg orally once per day
12 years: 2 to 3 mcg/kg or greater than or equal to 150 mcg orally once per day
Patients in which growth and puberty are complete: 1.7 mcg/kg orally once per day.
For chronic or severe hypothyroidism: 25 mcg orally once per day and increase dosage as needed in increments of 25 mcg every 2 to 4 weeks until the desired effect is achieved.
Comment:
- Hyperactivity in older children may be minimized by starting at one-quarter of the recommended dose and increasing each week by that amount until the full dose is achieved (4 weeks).
-The relative bioavailability between the injection and oral products has not been established. Therefore, caution should be used when switching patients from oral products to the injection as accurate dosing conversion has not been studied.
-A prospective randomized crossover study demonstrated that Syntroxine and an AB-rated generic L-T4 are not bioequivalent for patients less than 3 years of age with severe congenital hypothyroidism.
Parenteral:
The usual IV or IM dose is 50 to 75% of the oral dose.
Select the most affordable brand or generic drug
| Strength | Quantity | Price, USD | Country |
| Almox | |||
| ALMOX Liquid / 125mg per 5ml (60ml units) | $0.22 | Alkem Laboratories | |
| ALMOX 125 MG DRY SYRUP 1 bottle(s) (30 ML dry syrup each) | $0.25 | Alkem Laboratories Ltd | |
| Almox 250mg Capsule | $0.04 | Alkem Laboratories Ltd | |
| ALMOX 250MG CAPSULE 1 strip(s) (10 capsules each) | $0.43 | Alkem Laboratories Ltd | |
| ALMOX Capsule/ Tablet / 250mg (10 units) | $0.50 | Alkem Laboratories | |
| ALMOX Capsule/ Tablet / 500mg (10 units) | $0.77 | Alkem Laboratories | |
| Almox 250mg Tablet DT | $0.09 | Alkem Laboratories Ltd | |
| Almox 0.5% w/v EYE-DPS / 10ml | $0.95 | ||
| ALMOX 500 MG CAPSULE 1 strip(s) (10 capsules each) | $0.96 | Alkem Laboratories Ltd | |
| Almox 500mg Capsule | $0.10 | Alkem Laboratories Ltd | |
| Berlthyrox | |||
| Cynocuatro | |||
| Eurolev | |||
| Euthyrox N | |||
| Eutroid L | |||
| Goldshield Levothyroxine | |||
| L Thiroxin Berlin-Chemie | |||
| L- Thyrolevi | |||
| L-Thyrox HEXAL | |||
| L-Thyroxin AL | |||
| L-Thyroxin Berlin | |||
| L-Thyroxin Farmak | |||
| L-Thyroxin beta | |||
| L-Thyroxin-Na AbZ | |||
| L-Thyroxine Sandoz | |||
| Letrox | |||
| Levolet | |||
| LEVOLET tab 750 mg x 10's | $1.81 | Ikon | |
| LEVOLET tab 250 mg x 10's | $0.69 | Ikon | |
| LEVOLET tab 500 mg x 10's | $1.25 | Ikon | |
| Levothyrox | |||
| Levothyroxine | |||
| 100 mcg | 90 | $26.84 | Canada, India, NZ, Singapore, Turkey, UK, USA |
| 100 mcg | 90 | $30.31 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 100 mcg | 90 | $37.40 | USA |
| 100 mcg | 112 | $33.90 | Australia, Canada, NZ, Singapore, Turkey |
| 112 mcg | 30 | $20.45 | USA |
| 112 mcg | 90 | $32.00 | Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 112 mcg | 90 | $34.87 | Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 125 mcg | 90 | $30.20 | USA |
| 125 mcg | 90 | $39.24 | Australia, Canada, NZ, Singapore, Turkey, UK, USA |
| 125 mcg | 90 | $39.64 | Australia, Canada, India, NZ, Turkey, Singapore, UK, USA |
| 125 mcg | 100 | $33.00 | USA |
| 137 mcg | 90 | $32.57 | Australia, Canada, India, Mauritius, NZ, Turkey, Singapore, UK, USA |
| 137 mcg | 90 | $33.17 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 150 mcg | 30 | $7.00 | |
| 150 mcg | 90 | $32.00 | Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 150 mcg | 90 | $36.34 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 150 mcg | 90 | $39.40 | USA |
| 150 mcg | 100 | $40.38 | Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 150 mcg | 100 | $40.38 | Australia, Canada, India, NZ, Turkey, Singapore, UK, USA |
| 175 mcg | 90 | $36.49 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 175 mcg | 90 | $36.58 | Canada, India, NZ, Singapore, Turkey, UK, USA |
| 175 mcg | 90 | $40.15 | Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA |
| 200 mcg | 30 | $21.45 | USA |
| 200 mcg | 90 | $36.00 | Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 200 mcg | 90 | $38.22 | Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 25 mcg | 84 | $44.52 | Barbados, Canada, NZ, UK |
| 25 mcg | 90 | $27.56 | Australia, Canada, NZ, Singapore, Turkey, UK, USA |
| 25 mcg | 90 | $41.05 | USA |
| 25 mcg | 100 | $21.00 | Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 300 mcg | 90 | $49.40 | USA |
| 300 mcg | 100 | $45.66 | Canada, India, NZ, Singapore, Turkey, UK, USA |
| 300 mcg | 100 | $53.73 | Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA |
| 50 mcg | 28 | $23.48 | Barbados, Canada, NZ, UK |
| 50 mcg | 30 | $7.00 | |
| 50 mcg | 90 | $24.89 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 50 mcg | 90 | $28.76 | Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA |
| 75 mcg | 90 | $24.80 | USA |
| 75 mcg | 90 | $29.87 | Australia, Canada, NZ, Singapore, Turkey, UK, USA |
| 75 mcg | 90 | $30.17 | Australia, Canada, India, NZ, Turkey, Singapore, UK, USA |
| 75 mcg | 100 | $43.76 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 75 mcg | 100 | $59.59 | Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA |
| 88 mcg | 30 | $19.45 | USA |
| 88 mcg | 90 | $31.08 | Australia, Canada, India, NZ, Singapore, Turkey, UK, USA |
| 88 mcg | 90 | $33.89 | Australia, Canada, India, Mauritius, NZ, Turkey, Singapore, UK, USA |
| Eltroxin 0.05 mg Tablet | $0.03 | ||
| Eltroxin 0.3 mg Tablet | $0.07 | ||
| Synthroid 0.075 mg Tablet | $0.10 | ||
| Synthroid 0.3 mg Tablet | $0.12 | ||
| Levothyroxine 75 mcg tablet | $0.20 | ||
| Levothroid 25 mcg tablet | $0.31 | ||
| Levothroid 112 mcg tablet | $0.34 | ||
| Levothroid 175 mcg tablet | $0.38 | ||
| Unithroid direct 112 mcg tablet | $0.42 | ||
| Unithroid direct 25 mcg tablet | $0.42 | ||
| Levothyroxine Sodium 25 mcg tablet | $0.43 | ||
| Levothyroxine Sodium 112 mcg tablet | $0.46 | ||
| Unithroid 100 mcg tablet | $0.47 | ||
| Levothyroxine Sodium 150 mcg tablet | $0.50 | ||
| Unithroid 112 mcg tablet | $0.53 | ||
| Levothyroxine Sodium 175 mcg tablet | $0.57 | ||
| Synthroid 25 mcg tablet | $0.61 | ||
| Levoxyl 175 mcg tablet | $0.69 | ||
| Synthroid 100 mcg tablet | $0.73 | ||
| Synthroid 137 mcg tablet | $0.87 | ||
| Levoxyl 300 mcg tablet | $2.34 | ||
| Levothyroxine 100 mcg x 28's | $2.07 | ||
| Levothyroxine Actavis | |||
| Levothyroxine Clinipharm | |||
| Levothyroxine Mercury Pharma | |||
| Levothyroxine Na | |||
| Levothyroxine Nycomed | |||
| Levothyroxine P & D | |||
| Levothyroxine Sodium Vale | |||
| Levothyroxine Teva | |||
| Levothyroxine natrium Uni-Pharma | |||
| Levothyroxine solution | |||
| Levotiroteg | |||
| Levotiroxina Northia | |||
| Levotiroxina Puntanos | |||
| Levotiroxina Sodica American Generics | |||
| Levotiroxina Sódica | |||
| Levotiroxina Sódica Ratiopharm | |||
| Levotiroxina Teva | |||
| Levotyroxin | |||
| Medithyrox | |||
| Mercury Pharma Levothyroxine | |||
| Neothyron | |||
| Soloxine | |||
| 0 .1mg | 250 | $19.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .1mg | 250 | $19.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .2mg | 250 | $21.49 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .2mg | 250 | $21.49 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .3mg | 250 | $26.49 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .3mg | 250 | $26.49 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .5mg | 250 | $34.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .5mg | 250 | $34.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .8mg | 250 | $45.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| 0 .8mg | 250 | $45.99 | Canada, Mauritius, Singapore, Turkey, UK, USA |
| Synthyroid | |||
| Synthyroxine | |||
| T4 | |||
| Tamidan | |||
| Thiroyd | |||
| Thyrax | |||
| Thyrax 100 mcg x 100's | $12.22 | ||
| Thyrax Duotab | |||
| Thyroid-S | |||
| Thyronorm (12.5 mg) | |||
| Thyronorm 100mcg Tablet | $0.02 | Abbott India Ltd | |
| Thyronorm 75 mcg Tablet | $0.02 | ||
| Thyronorm 150 mcg Tablet | $0.02 | ||
| Thyronorm 112mcg Tablet | $0.02 | Abbott India Ltd | |
| 25 mcg x 100's | $1.57 | ||
| Thyronorm 50mcg TAB / 100 | $1.64 | ||
| Thyronorm 100mcg TAB / 100 | $1.75 | ||
| 150 mcg x 100's | $1.95 | ||
| THYRONORM 88MCG TABLET 1 packet(s) (100 tablets each) | $2.09 | Abbott India Ltd | |
| THYRONORM tab 150 mcg x 100's | $2.34 | Abbott | |
| THYRONORM 112 MCG TABLET 1 packet(s) (50 tablets each) | $1.18 | Abbott India Ltd | |
| Thyronorm (125mg) | |||
| Thyronorm 50mcg Tablet | $0.01 | Abbott India Ltd | |
| Thyronorm 25 mcg Tablet | $0.02 | ||
| Thyronorm 50 mcg Tablet | $0.02 | ||
| Thyronorm 62.5mcg Tablet | $0.02 | Abbott India Ltd | |
| THYRONORM Capsule/ Tablet / 100mcg (100 units) | $1.48 | Abbott India | |
| THYRONORM tab 50 mcg x 100's | $1.64 | Abbott | |
| 100 mcg x 100's | $1.75 | ||
| Thyronorm 125mcg TAB / 100 | $1.93 | ||
| THYRONORM 125 MCG TABLET 1 packet(s) (100 tablets each) | $2.09 | Abbott India Ltd | |
| THYRONORM tab 125 mcg x 100's | $2.34 | Abbott | |
| THYRONORM tab 12.5 mcg x 50's | $1.11 | Abbott | |
| Thyrorich | |||
| Thyrorich 100mcg Tablet | $0.02 | Primus Pharmaceuticals | |
| THYRORICH 25 MCG TABLET 1 packet(s) (100 tablets each) | $1.51 | Primus Pharmaceuticals | |
| THYRORICH 88MCG TABLET 1 packet(s) (100 tablets each) | $1.79 | Primus Pharmaceuticals | |
| THYRORICH tab 50 mcg x 100's | $1.34 | Primus Remedies | |
| Thyrosit | |||
| Thyrowin | |||
| Thyrowin 25 mcg Tablet | $0.01 | ||
| 25 mcg x 100's | $0.77 | ||
| THYROWIN 50MG TABLET 1 strip(s) (14 tablets each) | $0.99 | Abbott India Ltd | |
| Thyroxin | |||
| Thyroxine Actavis | |||
| Thyroxine-Lam Thong | |||
| Tirogal | |||
| Tivoral | |||
| Tozot | |||
| You Xian | |||
Syntroxine - Frequently asked Questions
Can Syntroxine be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Syntroxine?
Syntroxine should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of Syntroxine, especially if you are taking any other weight-loss medications or appetite suppressants.
Since thyroid hormone occurs naturally in the body, almost anyone can take Syntroxine. However, you may not be able to take this medication if you have certain medical conditions.
To make sure Syntroxine is safe for you, tell your doctor if you have:
-
a thyroid disorder called thyrotoxicosis;
-
heart disease, coronary artery disease, or a history of blood clots;
-
diabetes ;
-
anemia (lack of red blood cells);
-
osteoporosis, or low bone mineral density;
-
problems with your pituitary gland;
-
any food or drug allergies;
-
an untreated or uncontrolled adrenal gland disorder; or
-
if you have recently had a heart attack, or are having any symptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).
Tell your doctor if you have recently received radiation therapy with iodine (such as I-131).
FDA pregnancy category A. Syntroxine is not expected to harm an unborn baby. If you become pregnant while taking Syntroxine, do not stop taking the medicine without your doctor's advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy.
Syntroxine can pass into breast milk, but it is not expected to be harmful to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Your dose needs may be different while you are nursing.
What other drugs will affect Syntroxine?
Many other medicines can be affected by your thyroid hormone levels. Other medicine may also increase or decrease the effects of Syntroxine.
Many drugs can interact with Syntroxine and not all possible interactions are listed in this medication guide.
Tell your doctor about all medications you use, start using, or stop using during your treatment with Syntroxine. This includes prescription, over-the-counter, vitamin, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
How should I take Syntroxine?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Do not share this medication with another person, even if they have the same symptoms you have.
Syntroxine works best if you take it on an empty stomach, at least 30 minutes before breakfast. Follow your doctor's dosing instructions and try to take the medicine at the same time each day.
It is very important to take Syntroxine with a full glass (8 ounces) of water. The Syntroxine tablet can dissolve very quickly and swell in the throat, possibly causing choking or gagging.
While using Syntroxine, you may need frequent medical tests.
Tell any doctor or dentist who treats you that you are using Syntroxine.
Store at room temperature away from moisture and heat.
It may take several weeks before your body starts to respond to Syntroxine. Keep using this medicine even if you feel well. You may need to use Syntroxine for the rest of your life to replace the thyroid hormone your body cannot produce.
Can Syntroxine be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Syntroxine be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
Reviews
Following the study conducted by gmedication.com on Syntroxine, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Syntroxine. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.Patient reports
Patient reported useful
No survey data has been collected yetPatient reported side effects
No survey data has been collected yetPatient reported price estimates
No survey data has been collected yetFour patients reported frequency of use
How often should I take Syntroxine?According to the survey, gmedication.com reported that users of Syntroxine should take Once in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
| Patients | % | ||
|---|---|---|---|
| Once in a day | 4 | 100.0% | |
Two patients reported doses
What is the specific doses you have used?Syntroxine May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
| Patients | % | ||
|---|---|---|---|
| 51-100mg | 2 | 100.0% | |
Patient reported time for results
No survey data has been collected yetPatient reported administration
No survey data has been collected yetTwo patients reported age
| Patients | % | ||
|---|---|---|---|
| 46-60 | 2 | 100.0% | |
Patient reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Vishal Pawar, MD Pharmacology