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Simvastatine A |
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Here is the some steps to help you to save money on Simvastatine A purchase.
Read drug prescription
It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Simvastatine A before taking it.
What is Simvastatine A
Simvastatine A is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatine A reduces levels of "bad" cholesterol and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).Simvastatine A is used to lower cholesterol and triglycerides (types of fat) in the blood.
Simvastatine A is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Simvastatine A is used in adults and children who are at least 10 years old.
Simvastatine A may also be used for purposes not listed in Simvastatine A guide.
Simvastatine A side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.In rare cases, Simvastatine A can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
- signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or
- liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice.
Common side effects may include:
- headache;
- constipation, nausea, stomach pain; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Simvastatine A dosing
Usual Adult Dose for Prevention of Cardiovascular Disease:
Usual dosage range: 5 to 40 mg orally once a day in the eveningPatients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy, particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.
Usual Adult Dose for Cardiovascular Risk Reduction:
Usual dosage range: 5 to 40 mg orally once a day in the eveningPatients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy (including rhabdomyolysis), particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.
Usual Adult Dose for Homozygous Familial Hypercholesterolemia:
Recommended dose: 40 mg orally once a day in the eveningComments:
-Simvastatin should be used as an adjunct to other lipid-lowering treatments or alone if such treatments are unavailable.
Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:
Less than 10 years: Not recommended10 years or older:
Initial dose: 10 mg orally once a day in the evening
Maintenance dose: 10 to 40 mg orally once a day in the evening
Maximum dose: 40 mg orally once a day in the evening
Comments:
-Doses should be individualized according to the goal of therapy.
-Dose adjustments should be made at intervals of 4 weeks or more.
-Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment.
Approved indication:
-As an adjunct to diet to reduce total-C, LDL-C, and Apo B levels in adolescent boys and girls who are at least one year postmenarche, 10 to 17 years of age, with HeFH, if after an adequate trial of diet therapy the following findings are present:
1. LDL cholesterol remains 190 mg/dL or greater; or
2. LDL cholesterol remains 160 mg/dL or greater and there is a positive family history of premature cardiovascular disease (CVD) or two or more other CVD risk factors are present in the adolescent patient. The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C less than 130 mg/dL.
-The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.
Select the most affordable brand or generic drug
Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.