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What is Simtanin

Simtanin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simtanin reduces levels of "bad" cholesterol and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Simtanin is used to lower cholesterol and triglycerides (types of fat) in the blood.
Simtanin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Simtanin is used in adults and children who are at least 10 years old.
Simtanin may also be used for purposes not listed in Simtanin guide.

Simtanin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
In rare cases, Simtanin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Simtanin dosing

Usual Adult Dose for Prevention of Cardiovascular Disease:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy, particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Cardiovascular Risk Reduction:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy (including rhabdomyolysis), particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Homozygous Familial Hypercholesterolemia:

Recommended dose: 40 mg orally once a day in the evening
Comments:
-Simvastatin should be used as an adjunct to other lipid-lowering treatments or alone if such treatments are unavailable.

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

Less than 10 years: Not recommended
10 years or older:
Initial dose: 10 mg orally once a day in the evening
Maintenance dose: 10 to 40 mg orally once a day in the evening
Maximum dose: 40 mg orally once a day in the evening
Comments:
-Doses should be individualized according to the goal of therapy.
-Dose adjustments should be made at intervals of 4 weeks or more.
-Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment.
Approved indication:
-As an adjunct to diet to reduce total-C, LDL-C, and Apo B levels in adolescent boys and girls who are at least one year postmenarche, 10 to 17 years of age, with HeFH, if after an adequate trial of diet therapy the following findings are present:
1. LDL cholesterol remains 190 mg/dL or greater; or
2. LDL cholesterol remains 160 mg/dL or greater and there is a positive family history of premature cardiovascular disease (CVD) or two or more other CVD risk factors are present in the adolescent patient. The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C less than 130 mg/dL.
-The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
BIOSIM 5MG TABLET 1 strip(s) (10 tablets each) $0.27Biochem Pharmaceutical Industries
Biosim 5 mg Tablet $0.04
BIOSIM tab 10 mg x 10's $0.76Biochem
Biosim 20 mg Tablet $0.14
200 mg x 7's $1.58
LIPICARD 160 MG TABLET 1 strip(s) (10 tablets each) $1.64USV Ltd
160 mg x 7's $1.09
Mersivas 10 mg x 3 x 10's $14.65
Orovas 20 mg x 100's $38.89
Orovas 40 mg x 100's $51.11
Phalol 10 mg x 3 x 10's $6.51
10 mg10 Tablet$0.56
Satin 10 mg Tablet $0.06
Satin 10 mg Hinglaj Labs Tablet $0.06
Satin 10mg TAB / 10 $0.56
Satin 10mg Tablet $0.07Unichem Laboratories Ltd
SATIN 10MG TABLET 1 strip(s) (10 tablets each) $0.71Unichem Laboratories Ltd
Satin 20 mg Tablet $0.10
Satin 20mg TAB / 10 $0.97
Simbado 5 mg x 30's $4.44
Simbado 10 mg x 30's $6.66
SIMCARD Capsule/ Tablet / 20mg (10 units) $1.97Cipla
SIMCARD 20 MG TABLET 1 strip(s) (10 tablets each) $2.43Cipla Ltd
SIMCARD Capsule/ Tablet / 10mg (10 units) $1.20Cipla
SIMLO tab 20 mg x 10's $2.29IPCA
Simlo 5mg Tablet $0.07Ipca Laboratories Ltd
SIMLO Capsule/ Tablet / 10mg (10 units) $0.84IPCA Laboratories
20 mg10 Tablet$1.96
Simstat 20mg TAB / 10 $1.96
Simstat 5mg TAB / 10 $0.70
Simstat 10mg TAB / 10 $1.12
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References

  1. Dailymed."Simvastatin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Simvastatin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Simvastatin". http://www.drugbank.ca/drugs/DB0064... (accessed August 28, 2018).

Simtanin - Frequently asked Questions

Can Simtanin be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Simtanin?

Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Simtanin is usually taken at bedtime or with an evening meal. If you take Simtanin more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Simtanin, you may need frequent blood tests at your doctor's office.

You may need to take Simtanin on a long-term basis for the treatment of high cholesterol. You may need to stop using Simtanin for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Simtanin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Who should not take Simtanin?

You should not take Simtanin if you are allergic to it, if you are pregnant or breast-feeding, or if you have active liver disease.

The following drugs can increase your risk of serious muscle problems if you take them together with Simtanin. These drugs should not be used while you are taking Simtanin:

Before you start taking Simtanin, tell your doctor if you are already using any of these other medicines:

To make sure Simtanin is safe for you, tell your doctor if you have:

Simtanin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take Simtanin if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking Simtanin.

Simtanin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Simtanin.

What other drugs will affect Simtanin?

Many drugs can interact with Simtanin. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Simtanin, especially:

This list is not complete and many other drugs can interact with Simtanin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Can Simtanin be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Simtanin be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Simtanin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Simtanin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology