What is the medium of administration of the drug?
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Here is the some steps to help you to save money on Nitro-SR purchase.


Read drug prescription

It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Nitro-SR before taking it.

What is Nitro-SR

Nitro-SR is in a group of drugs called nitrates. Nitro-SR dilates blood vessels, making it easier for blood to flow through them and easier for the heart to pump.
Nitro-SR is used to treat or prevent attacks of chest pain (angina).
Nitro-SR may also be used for purposes not listed in Nitro-SR guide.

Nitro-SR side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Seek emergency medical attention if you have symptoms of a heart attack, such as:

Nitro-SR can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use Nitro-SR. Do not stop taking this medicine. Ask your doctor before using any headache pain medication.
Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Nitro-SR dosing

Usual Adult Dose for Angina Pectoris:

For relief of acute anginal attack:
Lingual spray: 1 to 2 sprays onto or under the tongue every 3 to 5 minutes as needed, up to 3 sprays in 15 minutes. If pain persists after the maximum number of doses, prompt medical attention is recommended.
Sublingual tablet: 0.3 to 0.6 mg dissolved under the tongue or in the Nitro-SR pouch every 5 minutes as needed, up to 3 doses in 15 minutes. If pain persists after the maximum number of doses, prompt medical attention is recommended.
IV continuous infusion (via non PVC tubing): 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed, up to a usual maximum of 200 and generally no more than 400 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Angina Pectoris Prophylaxis:

Lingual spray: 1 to 2 sprays (0.4 to 0.8 mg) onto or under the tongue 5 to 10 minutes prior to engaging in activities which might precipitate an acute attack
Sublingual tablet: 0.3 to 0.6 mg dissolved under the tongue or in the Nitro-SR pouch 5 to 10 minutes prior to engaging in activities which might precipitate an acute attack
Topical ointment: 1/2 inch initially, applied to a non hairy area of the trunk every 6 to 8 hours during waking hours (2 times a day); titrate as needed and tolerated. If angina occurs while the ointment is in place, the dose should be increased; if angina occurs several hours after application, the dosing frequency should be increased. Usual range is 1/2 to 2 inches (7.5 to 30 mg) every 8 hours, typically applied to 36 square inches of truncal skin.
Transdermal patch: 0.1 to 0.4 mg/hr patch applied to a dry and hairless area of the upper arm or body for 12 to 14 hours per day; titrate as needed and tolerated up to 0.8 mg/hr. Application sites should be rotated to avoid skin irritation.
Transmucosal (buccal) tablet: 1 mg dissolved between the lip and gum above the upper incisors or between the cheek and gum every 3 to 5 hours during waking hours (approximately 3 times a day); titrate as needed and tolerated. If angina occurs while a tablet is in place, the dose should be increased to the next strength; if angina occurs after dissolution of tablet, the dosing frequency should be increased. Usual maintenance dosage is 2 mg three times a day. If an acute attack occurs while a tablet is in place, another tablet may be administered on the opposite side from the one already in place. Sublingual Nitro-SR is recommended if prompt relief is not attained.
Oral: 2.5 every 8 to 12 hours; titrate as needed and tolerated up to 9 mg every 8 to 12 hours
Because tolerance to Nitro-SR may develop if plasma levels are maintained continuously, a nitrate free interval of 10 to 12 hours per day may be appropriate during chronic prophylaxis of angina pectoris. However, clinical studies suggest that such intermittent use may be associated with hemodynamic rebound during drug withdrawal and decreased exercise tolerance during the latter part of the nitrate free interval. Although the clinical relevance of this observation is unknown, a potentially increased risk of anginal attack during the nitrate free interval should be considered. Therefore, dosing regimens should be carefully individualized to each patient. Other antianginal drugs such as beta-blockers and calcium channel blockers may be prescribed to reduce the risk of aggravating myocardial ischemia during the drug free intervals.

Usual Adult Dose for Congestive Heart Failure:

Topical ointment: 1/2 inch initially, applied to a non hairy area of the trunk every 6 to 8 hours during waking hours ; titrate as needed and tolerated. Usual range is 1/2 to 2 inches (7.5 to 30 mg) every 8 hours, typically applied to 36 square inches of truncal skin.
Transdermal patch: 0.1 to 0.4 mg/hr patch applied to a dry and hairless area of the upper arm or body for 12 to 14 hours per day; titrate as needed and tolerated up to 0.8 mg/hr. Application sites should be rotated to avoid skin irritation.
Transmucosal (buccal) tablet: 1 mg dissolved between the lip and gum above the upper incisors or between the cheek and gum every 3 to 5 hours during waking hours (approximately 3 times a day); titrate as needed and tolerated. Usual maintenance dosage is 2 mg three times a day.
Oral: 2.5 every 8 to 12 hours; titrate as needed and tolerated up to 9 mg every 8 to 12 hours

Usual Adult Dose for Myocardial Infarction:

For the initial 24 to 48 hours after an acute myocardial infarction:
IV continuous infusion (via non PVC tubing): 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed up to a usual maximum of 200 and generally no more than 400 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Hypertension:

IV continuous infusion : 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed up to a usual maximum of 100 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Anal Fissure and Fistula:

For the treatment of moderate to severe pain associated with chronic anal fissure:
Apply 1 inch of ointment (375 mg of ointment equivalent to 1.5 mg of Nitro-SR) intra anally every 12 hours for up to 3 weeks.

Usual Pediatric Dose for Hypertension:

Perioperative hypertension or induction of intraoperative hypotension:
IV continuous infusion: 0.25 to 0.5 mcg/kg/min initially, increase by 0.5 to 1 mcg/kg/min every 3 to 5 minutes as needed up to 5 mcg/kg/min. Usual dose is 1 to 3 mcg/kg/min, but doses as high as 20 mcg/kg/min have been used.

Select the most affordable brand or generic drug

Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

StrengthQuantityPrice, USDCountry
Glyceryl Trinitrate DBL 50 mg/10 mL x 5's $7.03
Glytrin 20mg Tablet $0.14Medley Pharmaceuticals
GLYTRIN 20MG TABLET 1 strip(s) (10 tablets each) $1.39Medley Pharmaceuticals
GLYTRIN TABLET 20MG 1 strip(s) (10 tablets each) $1.39Medley Pharmaceuticals
2 %ointment1 x30gtube$44.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 %ointment1 x30gtube$45.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 %ointment1 x60gtube$69.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 %ointment1 x60gtube$70.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 %60 gram$79.55Barbados, Canada, NZ, UK
2 %60 gram$79.55Barbados, Canada, NZ, UK
2 %120 g$159.10Barbados, Canada, NZ, UK
0 .6mg100 $52.03Barbados, Canada, NZ, UK
0 .6mg100 $52.03Barbados, Canada, NZ, UK
0 .6mg100 $52.03Barbados, Canada, NZ, UK
Perlinganit 10 mg/10 mL x 10's $70.25
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References

  1. Dailymed."Nitroglycerin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Nitroglycerin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Nitroglycerin". http://www.drugbank.ca/drugs/DB0072... (accessed August 28, 2018).

Nitro-SR - Frequently asked Questions

Can Nitro-SR be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Nitro-SR?

You should not use Nitro-SR if you are allergic to it, or if:

Do not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking Nitro-SR. Using erectile dysfunction medicine with Nitro-SR can cause a sudden and serious decrease in blood pressure.

You should not use sublingual Nitro-SR if you have:

To make sure Nitro-SR is safe for you, tell your doctor if you have:

FDA pregnancy category C. It is not known whether Nitro-SR will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether Nitro-SR passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Nitro-SR?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Keep this medicine on hand at all times in case of an angina attack. Get your prescription refilled before you run out of medicine completely.

Nitro-SR is usually taken at the first sign of chest pain. If possible, try to rest or stay seated when you use this medication. Nitro-SR can cause dizziness or fainting.

You may use Nitro-SR sublingual within 5 to 10 minutes before an activity you think might cause chest pain. Follow your doctor's instructions.

If you use Nitro-SR sublingual spray to treat an angina attack: At the first sign of an attack, apply the spray directly on or under your tongue. Close your mouth after each spray. Do not inhale the spray. Do not shake the spray before or during use. You may use additional sprays every 5 minutes, but not more than 3 sprays in 15 minutes.

The Nitro-SR sublingual tablet should be placed under your tongue and allowed to dissolve slowly. Do not chew or swallow it. You may use additional tablets every 5 minutes, but not more than 3 tablets in 15 minutes.

Seek emergency medical attention if your chest pain gets worse or lasts more than 5 minutes, especially if you have trouble breathing or feel weak, dizzy, or nauseated, or lightheaded.

You may feel a slight burning or stinging in your mouth when you use this medicine. However, this sensation is not a sign of how well the medication is working. Do not use more medication just because you do not feel a burning or stinging.

Do not crush, chew, break, or open an extended-release capsule. Swallow it whole.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Nitro-SR.

If you take Nitro-SR on a regular schedule to prevent angina, do not stop taking it suddenly or you could have a severe attack of angina.

Store the tablets in the glass container at room temperature, away from moisture and heat. Keep the bottle tightly closed when not in use.

Keep the spray away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot.

What other drugs will affect Nitro-SR?

Many drugs can interact with Nitro-SR. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Nitro-SR, especially:

This list is not complete and many other drugs can interact with Nitro-SR. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Can Nitro-SR be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Nitro-SR be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Nitro-SR, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Nitro-SR. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


One patient reported side effects

Does the Nitro-SR Have Any Side Effects?
Based on the survey report from users of gmedication.com, about No side effects number of people suffered some side effect after consumption of Nitro-SR. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Nitro-SR.
Patients%
No side effects1
100.0%


Patient reported price estimates

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Patient reported frequency of use

No survey data has been collected yet


Patient reported doses

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The information was verified by Dr. Vishal Pawar, MD Pharmacology