Nexavar

Rating: 2.5 - 2 review(s)
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Here is the some steps to help you to save money on Nexavar purchase.


Read drug prescription

infoIt is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Nexavar before taking it.

Nexavar

What is Nexavar

Nexavar is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Nexavar is used to treat liver cancer, thyroid cancer, or a type of kidney cancer called advanced renal cell carcinoma.
Nexavar may also be used for purposes not listed in Nexavar guide.

Nexavar side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Nexavar and call your doctor at once if you have:
  • mouth sores;
  • blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;
  • heavy menstrual periods, easy bruising, unusual bleeding, or any bleeding that will not stop;
  • pale skin, feeling light-headed, rapid heart rate, trouble concentrating;
  • dry cough, wheezing;
  • chest pain and severe dizziness, fainting, sweating, swelling, rapid weight gain, feeling short of breath (even with mild exertion);
  • rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
  • upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • sudden weight loss, increased appetite, trouble sleeping, increased bowel movements, feeling hot, feeling nervous or anxious, swelling in your neck (goiter);
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, confusion, uneven heartbeats, seizure); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:
  • tired feeling;
  • vomiting, diarrhea, mild stomach pain;
  • mild itching or rash; or
  • weight loss, thinning hair.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Nexavar dosing

Usual Adult Dose for Renal Cell Carcinoma:

400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.

Usual Adult Dose for Thyroid Cancer:

400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.

Usual Adult Dose for Hepatocellular Carcinoma:

400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.
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Compare prices at online shops

infoPrices of the drug can vary in different shops. There will be a variation in price from pharmacy to an online shop. Most online shops will have a little lower price when compared to pharmacy stores, so you need to cross check before buying. Just go to a nearest pharmacy store and check for prices before you decide on buying. You should also be checking and comparing prices among various online stores and should be choosing the affordable and best store. The prices also vary based on brands, and you should note few stores sell specific brands, and you should learn to compare prices of same brand in different stores. Below are the prices of Nexavar medicine in some well-known online stores.

StrengthQuantityPrice, USDCountry
200 mg120 $7.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
200 mg112 $3.00Canada, Mauritius, Singapore, Turkey, UK, USA
200 mg120 $7.00Barbados, Canada, NZ, UK


Select the most affordable brand or generic drug

infoGeneric drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

StrengthQuantityPrice, USDCountry
200 mg30 $458.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
200 mg90 $899.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA

References

  1. Cancer.Net."Angiogenesis and angiogenesis inhibitors to treat cancer". http://www.cancer.net/navigating-cancer-... (accessed September 10, 2018).
  2. "Sorafenib". http://www.drugbank.ca/drugs/DB00398 (accessed September 10, 2018).
  3. "Sorafenib". https://pubchem.ncbi.nlm.nih.gov/compoun... (accessed September 10, 2018).
  4. "Antineoplastic agents". https://www.ncbi.nlm.nih.gov/mesh/680009... (accessed September 10, 2018).
  5. "Sorafenib: link to the compound information in wikipedia.". https://en.wikipedia.org/wiki/Sorafenib (accessed September 10, 2018).
  6. "Sorafenib". https://toxnet.nlm.nih.gov/cgi-bin/sis/s... (accessed September 10, 2018).
  7. "Sorafenib: nci thesaurus (ncit) provides reference terminology for many systems. it covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser/Con... (accessed September 10, 2018).
  8. "The cambridge structural database provides access to 3d structures of molecules determined experimentally using diffraction techniques.". http://www.ccdc.cam.ac.uk/pages/Home.asp... (accessed September 10, 2018).
  9. "Chebi ontology: the chebi ontology is a structured classification of the entities contained within chebi.". http://www.ebi.ac.uk/chebi/userManualFor... (accessed September 10, 2018).
  10. "Cytochrome p450 interactions". http://www.genome.jp/kegg-bin/get_htext?... (accessed September 10, 2018).
  11. "Sorafenib: the human metabolome database (hmdb) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB00145... (accessed September 10, 2018).
  12. "Sorafenib (by mouth): this section provide the link out information of drugs collectetd in pubmed health. ". http://www.ncbi.nlm.nih.gov/pubmedhealth... (accessed September 10, 2018).
  13. "International patent classification: the world intellectual property organization (wipo) international patent classification (ipc), established by the strasbourg agreement 1971, provides for a hierarchical system of language independent symbols for the classification of patents and utility models according to the different areas of technology to which they pertain.". http://www.wipo.int/classifications/ipc/ (accessed September 10, 2018).
  14. "Chemidplus chemical information classification: chemidplus is a toxnet (toxicology data network) databases that contain chemicals and drugs related information. it is managed by the toxicology and environmental health information program (tehip) in the division of specialized information services (sis) of the national library of medicine (nlm).". https://chem.sis.nlm.nih.gov/chemidplus/... (accessed September 10, 2018).
  15. "Sorafenib". https://clinicaltrials.gov/ (accessed September 10, 2018).

Nexavar - Frequently asked Questions

Can Nexavar be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Nexavar?

Nexavar is usually taken 2 times per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Nexavar on an empty stomach, at least 1 hour before or 2 hours after eating.

Do not crush, chew, or break a Nexavar tablet. Swallow it whole with water.

Your blood pressure will need to be checked often.

If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using Nexavar. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat.

Who should not take Nexavar?

You should not use Nexavar if you are allergic to it, or if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane).

To make sure Nexavar is safe for you, tell your doctor if you have:

  • kidney or liver problems other than cancer;

  • lung cancer;

  • a bleeding or blood clotting disorder such as hemophilia;

  • high blood pressure (hypertension), heart disease, slow heartbeats, congestive heart failure, chest pain;

  • a personal or family history of Long QT syndrome;

  • a history of stroke or heart attack; or

  • any allergies.

FDA pregnancy category D. Do not use Nexavar if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are receiving Nexavar, whether you are a man or a woman. Tell your doctor right away if a pregnancy occurs while either parent is taking this medication. Keep using birth control for at least 2 weeks after your treatment ends.

It is not known whether Nexavar passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

What other drugs will affect Nexavar?

Tell your doctor about all other cancer medicines you use, especially cisplatin, cyclophosphamide, docetaxel, doxorubicin, fluorouracil, gemcitabine, irinotecan, paclitaxel, or tamoxifen.

Many drugs can interact with Nexavar. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Nexavar, especially:

  • dexamethasone;

  • neomycin;

  • St. John's wort;

  • a blood thinner (warfarin, Coumadin);

  • seizure medication--carbamazepine, fosphenytoin, phenobarbital, phenytoin; or

  • tuberculosis medicine--rifabutin, rifampin.

This list is not complete and many other drugs can interact with Nexavar. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Can Nexavar be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Nexavar be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by wDrugs.com on Nexavar, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Nexavar. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

One patient reported side effects

Does the Nexavar Have Any Side Effects?
Based on the survey report from users of wDrugs.com, about No side effects number of people suffered some side effect after consumption of Nexavar. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Nexavar.
Patients%
No side effects1
100.0%

One patient reported price estimates

Do you think The Price of Nexavar is Worth It?
Do you feel you paid higher than the value you got from it after usage? According to reports from wDrugs.com users, on whether the Nexavar medicine is affordable, users shared different opinions on the question. The views concerning the price of the medicine were based on some factors like the brand the patient bought, the price compared to its level of effectiveness, the nation or country where the medicine is sold, and the amount of money the patient has. For users who are of the opinion that the medicine is unaffordable, they may have to consider a medicine with another brand in a bid to reduce cost.
Patients%
Expensive1
100.0%

Two patients reported doses

What is the specific doses you have used?
Nexavar May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of wDrugs.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients%
101-200mg2
100.0%

One patient reported time for results

How long will I use Nexavar before I begin to notice the effect?
According to the report by users of wDrugs.com, about 3 month and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Nexavar. However, if you wish to get the response of other users on the time effectiveness of using Nexavar kindly click here
Patients%
3 month1
100.0%

Four patients reported age

Patients%
46-602
50.0%
> 602
50.0%

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The information was verified by Dr. Harshad Shah, MD Pharmacology