Myleran

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What is the medium of administration of the drug?

Here is the some steps to help you to save money on Myleran purchase.


Read drug prescription

infoIt is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Myleran before taking it.

Myleran

What is Myleran

Myleran is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Myleran taken by mouth is used to treat the symptoms of chronic myelogenous leukemia. Myleran injection is used together with a medicine called cyclophosphamide, to prepare your body to receive a stem cell transplant from a donor's bone marrow.
Myleran is not a cure for leukemia.
Myleran may also be used for purposes not listed in Myleran guide.

Myleran side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • coughing up blood;
  • hallucinations;
  • persistent cough, congestion, low fever, feeling short of breath (may occur several months or years after using Myleran).
  • seizure (convulsions);
  • adrenal gland problems (after long-term Myleran use)--nausea, vomiting, loss of appetite, weight loss and severe weakness or tired feeling;
  • low magnesium--unusual eye movements, muscle tightness or contraction, muscle weakness or limp feeling, numbness;
  • low platelets--easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling;
  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • low white blood cell counts--fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;
  • signs of a heart problem--stomach pain, vomiting, sharp chest pain, trouble breathing; or
  • signs of liver problems--weight gain, stomach swelling or tenderness, jaundice (yellowing of the skin or eyes).

Common side effects may include:
  • stomach pain, diarrhea, nausea, vomiting;
  • blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
  • fever;
  • low red blood cells, low potassium;
  • headache, weakness, anxiety;
  • skin rash;
  • sleep problems (insomnia); or
  • high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Myleran dosing

Usual Adult Dose for Chronic Myelogenous Leukemia:

Initial dose: 60 mcg/kg or 1.8 mg/m2 orally once a day. The usual dosage range for remission induction is 4 to 8 mg/day.

Usual Adult Dose for Bone Marrow Transplantation:

2 to 4 mg/kg orally every 6 hours for 4 days. High dose cyclophosphamide has been used in combination with Myleran to prepare patients for bone marrow transplantation.

Usual Pediatric Dose for Chronic Myelogenous Leukemia:

Initial Dose:
Less than or equal to 12 kg : 1.1 mg/kg (based on actual body weight.)
Greater than 12 kg: 0.8 mg/kg (based on actual body weight.)
Doses are administered every 6 hours as 2 hour infusions over 4 days for a total of 16 doses.
Therapeutic drug monitoring and dose adjustment following the first dose is recommended.
Adjust subsequent doses to achieve the desired target AUC (1125 uM/min) using the formula below:
Adjusted Dose (mg) = Actual Dose (mg) x Target AUC (uM/min) / Actual AUC (uM/min)

Usual Pediatric Dose for Bone Marrow Transplantation:

Marrow-ablative conditioning regimen:
0.5 mg/kg to 1 mg/kg orally every 6 hours for 4 days.
Hematopoetic stem cell transplant program:
Less than or equal to 6 years:
40 mg/m2/dose every 6 hours for 4 days.
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Compare prices at online shops

infoPrices of the drug can vary in different shops. There will be a variation in price from pharmacy to an online shop. Most online shops will have a little lower price when compared to pharmacy stores, so you need to cross check before buying. Just go to a nearest pharmacy store and check for prices before you decide on buying. You should also be checking and comparing prices among various online stores and should be choosing the affordable and best store. The prices also vary based on brands, and you should note few stores sell specific brands, and you should learn to compare prices of same brand in different stores. Below are the prices of Myleran medicine in some well-known online stores.

StrengthQuantityPrice, USDCountry
2 mg100 $95.00Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 mg50 $75.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
2 mg25 $55.49Canada, Mauritius, Singapore, Turkey, UK, USA
2 mg100 $176.72Barbados, Canada, NZ, UK


There does not exist generic for this medicine.

Reviews

Following the study conducted by wDrugs.com on Myleran, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Myleran. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

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Information checked by Dr. Shikha Narang, MD Pharmacology