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consists of Metronidazole, Spiramycin.

Metronidazole

What is Metronidazole

Metronidazole TABLETS USP
Metronidazole Injection USP, sterile, is a parenteral dosage form of a synthetic antibacterial agent, 2-methyl-5-nitroimidazole-1-ethanol.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Metronidazole Injection USP and other antibacterial drugs, Metronidazole Injection USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
TREATMENT OF ANAEROBIC INFECTIONS
Metronidazole Injection USP is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Indicated surgical procedures should be performed in conjunction with Metronidazole Injection USP therapy. In a mixed aerobic and anaerobic infection, antibiotics appropriate for the treatment of the aerobic infection should be used in addition to Metronidazole Injection USP.
Metronidazole Injection USP is effective in Bacteroides fragilis infections resistant to clindamycin, chloramphenicol, and penicillin.
Intra-Abdominal Infections, including peritonitis, intra-abdominal abscess, and liver abscess, caused by Bacteroides species including the B. fragilis group (B. fragilis, B. distasonis, B. ovatus, B. thetaiotaomicron, B. vulgatus), Clostridium species, Eubacterium species, Peptostreptococcus species, and Peptococcus niger.
Skin and Skin Structure Infections caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus niger, Peptostreptococcus species, and Fusobacterium species.
Gynecologic Infections, including endometritis, endomyometritis, tuboovarian abscess, and post-surgical vaginal cuff infection, caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus niger, and Peptostreptococcus species.
Bacterial Septicemia caused by Bacteroides species including the B. fragilis group and Clostridium species.
Bone and Joint Infections, as adjunctive therapy, caused by Bacteroides species including the B. fragilis group.
Central Nervous System (CNS) Infections, including meningitis and brain abscess, caused by Bacteroides species including the B. fragilis group.
Lower Respiratory Tract Infections, including pneumonia, empyema, and lung abscess, caused by Bacteroides species including the B. fragilis group.
Endocarditis caused by Bacteroides species including the B. fragilis group.
PROPHYLAXIS
The prophylactic administration of Metronidazole Injection USP preoperatively, intraoperatively, and postoperatively may reduce the incidence of postoperative infection in patients undergoing elective colorectal surgery which is classified as contaminated or potentially contaminated.
Prophylactic use of Metronidazole Injection USP should be discontinued within 12 hours after surgery. If there are signs of infection, specimens for cultures should be obtained for the identification of the causative organism(s) so that appropriate therapy may be given (see DOSAGE AND ADMINISTRATION).
Metronidazole is an usually used to treat. Some of the most prescribed drugs in this class include: Metronidazole (generic).

Spiramycin is an antibiotic, prescribed for different types of infection.

Spiramycin indications

Spiramycin is an antibiotic, prescribed for different types of infection.  

Spiramycin contraindication

Hypersensitivity.

Spiramycin dosage

Adult- Oral: The recommended dose is 1 to 2 grams two times per day or 500mg to 1gm three times per day.
Child: Dose is based on body weight. The recommended dose is 25mg/kg, two times per day.

Spiramycin usage

It comes as a tablet to take by mouth, with or without food.

Spiramycin precautions

Caution should be exercised in patients with history of abnormal heart rhythm or other heart diseases, liver impairment, any allergy, elderly, during pregnancy and breastfeeding.
Monitor liver function regularly while taking Spiramycin.

Spiramycin side effects

Gastrointestinal- Nausea, vomiting, abdominal pain and diarrhea.
Skin- Hives, itching and rashes.

Spiramycin warning

Avoid excess dosage.

Spiramycin storage conditions

Store it at room temperature and in an airtight container. Keep away from children.


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References

  1. Dailymed."Bismuth subcitrate potassium; metronidazole; tetracycline: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Metronidazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Metronidazole". http://www.drugbank.ca/drugs/DB0091... (accessed August 28, 2018).

Metronidazole/Spiramycin - Frequently asked Questions

Can Metronidazole/Spiramycin be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Can Metronidazole/Spiramycin be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Metronidazole/Spiramycin be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Metronidazole/Spiramycin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Metronidazole/Spiramycin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


One patient reported side effects

Does the Metronidazole/Spiramycin Have Any Side Effects?
Based on the survey report from users of gmedication.com, about No side effects number of people suffered some side effect after consumption of Metronidazole/Spiramycin. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Metronidazole/Spiramycin.
Patients%
No side effects1
100.0%


Patient reported price estimates

No survey data has been collected yet


Patient reported frequency of use

No survey data has been collected yet


Patient reported doses

No survey data has been collected yet


Patient reported time for results

No survey data has been collected yet


One patient reported administration

When is the best condition to take Metronidazole/Spiramycin: Before or after food?
Based on the survey, the users of gmedication.com voted that Metronidazole/Spiramycin is best taken at After food. It is however worthy of mention that this popular vote may not be an appropriate description for your particular health condition. See your doctor for professional medical advice as regards the best time to take this medicine. If you wish to see the views of other users on the best time to take the medicine, simply click here.
Patients%
After food1
100.0%


One patient reported age

Patients%
30-451
100.0%


Patient reviews


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The information was verified by Dr. Vishal Pawar, MD Pharmacology