Levofloxacino Combino

Name: Levofloxacino Combino Price Comparison: Uses, Dosage, Form & Side Effects
Creator: gmedication.com
Published: 2021-11-01T10:10:10+00:00

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Levofloxacino Combino side effects
Levofloxacino Combino dosing

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Frequently asked Questions

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What other drugs will affect Levofloxacino Combino?
Who should not take Levofloxacino Combino?

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What is Levofloxacino Combino

Levofloxacino Combino is in a group of antibiotics called fluoroquinolones. Levofloxacino Combino fights bacteria in the body.
Levofloxacino Combino is used to treat bacterial infections of the skin, sinuses, kidneys, bladder, or prostate. Levofloxacino Combino is also used to treat bacterial infections that cause bronchitis or pneumonia, and to treat people who have been exposed to anthrax or plague.
Levofloxacino Combino may also be used for purposes not listed in Levofloxacino Combino guide.

Levofloxacino Combino side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives, or the first sign of a skin rash; rapid heart rate, difficult breathing; swelling of your face, lips, tongue, or throat.
Levofloxacino Combino may cause swelling or tearing of (rupture) a tendon. Levofloxacino Combino can also have serious effects on your nerves, and may cause permanent nerve damage. Stop taking this medicine and call your doctor at once if you have:

signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions); or
nerve symptoms--numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position.

Stop using Levofloxacino Combino and call your doctor at once if you have:

headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
muscle weakness or trouble breathing;
diarrhea that is watery or bloody;
sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, easy bruising or bleeding;
depression, confusion, hallucinations, paranoia, tremors, feeling restless or anxious, unusual thoughts or behavior, insomnia, nightmares;
severe eye redness, small white or yellow patches on the surface of your eye;
seizure (convulsions); or
increased pressure inside the skull-- severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.

Common side effects may include:

constipation, mild diarrhea;
mild dizziness; or
mild headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Levofloxacino Combino dosing

Usual Adult Dose for Nosocomial Pneumonia:

750 mg orally or IV every 24 hours for 7 to 14 days
Initial empiric treatment with broad-spectrum coverage according to the hospital's and/or ICU's antibiogram is recommended if multidrug-resistant organisms are suspected.
Duration: If the causative organism is not Pseudomonas aeruginosa, the duration of treatment should be as short as clinically possible to reduce the risk of superinfections with resistant organisms.

Usual Adult Dose for Pneumonia:

Community-acquired pneumonia:
Due to methicillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae (including multi-drug resistant S pneumoniae [MDRSP]), Haemophilus influenzae, H parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydophila pneumoniae, Legionella pneumophila, or Mycoplasma pneumoniae: 500 mg orally or IV every 24 hours for 7 to 14 days
Due to S pneumoniae (excluding MDRSP), H influenzae, H parainfluenzae, M pneumoniae, or C pneumoniae: 750 mg orally or IV every 24 hours for 5 days

Usual Adult Dose for Sinusitis:

Acute bacterial sinusitis: 500 mg orally or IV every 24 hours for 10 to 14 days or 750 mg orally or IV every 24 hours for 5 days

Usual Adult Dose for Bronchitis:

Acute bacterial exacerbation of chronic bronchitis: 500 mg orally or IV once a day for 7 days

Usual Adult Dose for Skin or Soft Tissue Infection:

Uncomplicated: 500 mg orally or IV once a day for 7 to 10 days
Complicated: 750 mg orally or IV once a day for 7 to 14 days

Usual Adult Dose for Prostatitis:

Chronic bacterial prostatitis: 500 mg orally or IV every 24 hours for 28 days

Usual Adult Dose for Urinary Tract Infection:

Complicated:
Due to Enterococcus faecalis, Enterobacter cloacae, E coli, K pneumoniae, Proteus mirabilis, or Pseudomonas aeruginosa: 250 mg orally or IV once a day for 10 days
Due to E coli, K pneumoniae, or P mirabilis: 750 mg orally or IV once a day for 5 days
Uncomplicated: 250 mg orally or IV once a day for 3 days

Usual Adult Dose for Pyelonephritis:

Acute:
Due to Escherichia coli: 250 mg orally or IV once a day for 10 days
Due to E coli : 750 mg orally or IV once a day for 5 days

Usual Adult Dose for Cystitis:

250 mg orally or IV once a day for 3 days

Usual Adult Dose for Anthrax Prophylaxis:

Prophylaxis postexposure to inhalational Bacillus anthracis: 500 mg orally or IV once a day for 60 days after exposure

Usual Adult Dose for Plague:

For treatment of plague and prophylaxis for plague: 500 mg orally or IV once a day for 10 to 14 days
Drug administration should begin as soon as possible after suspected or confirmed exposure to Yersinia pestis. Higher doses (750 mg orally or IV once a day) can be used for treatment of plague if clinically indicated.

Usual Adult Dose for Plague Prophylaxis:

For treatment of plague (including pneumonic and septicemic plague) and prophylaxis for plague: 500 mg orally or IV once a day for 10 to 14 days
Drug administration should begin as soon as possible after suspected or confirmed exposure to Yersinia pestis. Higher doses (750 mg orally or IV once a day) can be used for treatment of plague if clinically indicated.

Usual Adult Dose for Inhalation Bacillus anthracis:

Mass casualty treatment: 500 mg orally or IV once a day for 60 days
The Working Group on Civilian Biodefense has suggested that, based on in vitro studies, Levofloxacino Combino could be used for treatment of inhalational anthrax if ciprofloxacin and doxycycline are not available. One or two additional antibiotics with activity against the causative organism (e.g., rifampin, vancomycin, penicillin, ampicillin, chloramphenicol, imipenem, clindamycin, or clarithromycin) should be added.

Usual Adult Dose for Tuberculosis -- Active:

(Not approved by FDA)
500 to 1000 mg orally or IV once a day
This regimen has been recommended by the Centers for Disease Control and Prevention (CDC), the Infectious Diseases Society of America, and American Thoracic Society.
May be given in combination with at least 3 other active drugs for treatment of multi-drug resistant TB, or when the patient is intolerant of first-line agents. AFB smear and culture should be monitored monthly.
Duration: Treatment for TB should generally continue for 18 to 24 months, or for 12 to 18 months after culture results are negative.

Usual Adult Dose for Nongonococcal Urethritis:

CDC recommendations: 500 mg orally once a day for 7 days
Levofloxacino Combino therapy is recommended as an alternative regimen. Single-dose azithromycin is a preferred regimen.
The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Chlamydia Infection:

(Not approved by FDA)
CDC recommendations: 500 mg orally once a day for 7 days
Levofloxacino Combino therapy is recommended as an alternative regimen. Single-dose azithromycin is a preferred regimen.
The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Pelvic Inflammatory Disease:

CDC recommendations:
Mild to moderately severe acute PID: 500 mg orally once a day for 14 days
Due to high rates of resistance, the CDC does not recommend fluoroquinolones for treatment of gonococcal infections in the United States. As a result, regimens that include a quinolone are not recommended for the treatment of PID. If parenteral cephalosporin therapy is not possible, oral Levofloxacino Combino (with or without oral metronidazole) can be considered if community prevalence and individual risk for gonorrhea are low. Prior to therapy, diagnostic tests for gonorrhea must be performed. If test results are positive for quinolone-resistant Neisseria gonorrhoeae and cephalosporin therapy is not possible, single-dose azithromycin should be added to this quinolone-based PID regimen.
If patients do not respond to oral therapy within 72 hours, they should be reevaluated and parenteral therapy should be initiated.

Usual Adult Dose for Epididymitis -- Sexually Transmitted:

(Not approved by FDA)
CDC recommendations: 500 mg orally once a day for 10 days
The patient's sexual partner(s) should also be evaluated/treated.
All patients should receive ceftriaxone plus doxycycline for initial (empiric) treatment. Additional therapy can include Levofloxacino Combino if testing determines acute epididymitis is not caused by gonorrhea or if the infection is most likely caused by enteric organisms.
Due to high rates of resistance, the CDC does not recommend fluoroquinolones for treatment of gonococcal infections in the United States. Ceftriaxone is the first-line agent recommended for the treatment of gonococcal infections in the United States. Antimicrobial susceptibility patterns should be monitored.

Usual Pediatric Dose for Anthrax Prophylaxis:

Prophylaxis postexposure to inhalational B anthracis:
6 months or older:
Less than 50 kg: 8 mg/kg orally or IV every 12 hours for 60 days; not to exceed 250 mg per dose
50 kg or more: 500 mg orally or IV every 24 hours for 60 days

Usual Pediatric Dose for Plague:

For treatment of plague and prophylaxis for plague:
6 months or older:
Less than 50 kg: 8 mg/kg orally or IV every 12 hours for 10 to 14 days; not to exceed 250 mg per dose
50 kg or more: 500 mg orally or IV every 24 hours for 10 to 14 days
Drug administration should begin as soon as possible after suspected or confirmed exposure to Yersinia pestis.

Usual Pediatric Dose for Plague Prophylaxis:

For treatment of plague (including pneumonic and septicemic plague) and prophylaxis for plague:
6 months or older:
Less than 50 kg: 8 mg/kg orally or IV every 12 hours for 10 to 14 days; not to exceed 250 mg per dose
50 kg or more: 500 mg orally or IV every 24 hours for 10 to 14 days
Drug administration should begin as soon as possible after suspected or confirmed exposure to Yersinia pestis.

Active ingredients: Levofloxacin

Select the most affordable brand or generic drug

Strength	Quantity	Price, USD	Country
An Shi Li
Anuar
Benur
Floxabact
L-Optic-Rompharm
L?vofloxacine Biogaran
L?vofloxacine Teva
L?vofloxacine Zentiva
L?vofloxacine Zydus
Lebel
Lefloxin
Lefloxin 500 mg x 50's		$1.40
Levex
Levocom
Levocom Tablet		$0.05	Commonwealth Pharmaceuticals
LEVOCOM TABLET 1 strip(s) (10 tablets each)		$0.51	Commonwealth Pharmaceuticals
LEVOCOM tab 250 mg x 10's		$0.70	Commonwealth
Levocom 250mg TAB / 10		$0.70
Levocom 500mg Tablet		$0.11	Commonwealth Pharmaceuticals
LEVOCOM tab 500 mg x 10's		$1.05	Commonwealth
Levocom 500mg TAB / 10		$1.05
LEVOCOM 500MG TABLET 1 strip(s) (10 tablets each)		$1.11	Commonwealth Pharmaceuticals
Levofloksasiini
Levofloxacin 0.5.% Nitten
Levofloxacin 0.5.% Towa
Levofloxacin 1.5.% Kaken
Levofloxacin 1.5.% Ohara
Levofloxacin 5 MG/ML Ophthalmic Solution [Quixin]
Levofloxacin FP
Levofloxacin Hanall
Levofloxacin STADA
Levofloxacin YD
Levofloxacin tablets
Levofloxacin-Winthrop
Levofloxacina Chiesi
Levofloxacine Bluefish
Levofloxacine Mylan
Levofloxacine Sandoz
Levomax
LEVOMAX tab 500 mg x 10's		$1.11	CE-Biotec
Levonidin
Levoquinol
Levoxal
Levoxal 500 mg/100 mL x 1's		$13.99
Levoxal 500 mg x 3 x 6's		$29.97
Levunid
Lewor
Lifuxing
Lin Yuan Fang Xin
Lévofloxacine Ranbaxy
Medcolev
Mepafloxin
Oftaquix
Oftaquix 0.5 % x 5 mL		$6.96
Orlev
Orlev 750 mg Tablet		$0.15
Orlev 500 mg Tablet		$0.13
Pharex Levofloxacin
Pharex Levofloxacin tab 750 mg 30's		$46.80	XL Lab
Pharex Levofloxacin tab 500 mg 30's		$0.98	XL Lab
Pu Ya Te
Qi Sheng
Quinolev
QUINOLEV tab 500 mg x 20's		$2.10	Minova
Quinolev 500 mg Tablet		$0.11
Reskuin
Reskuin 250 mg x 10's		$10.73
Reskuin 500 mg x 10's		$16.65
Safelevo
Safelevo 250mg Tablet		$0.05	MSN Laboratories
Safelevo 250mg FC-TAB / 10		$0.56
SAFELEVO film-coated tab 500 mg x 10's		$1.05	MSN Labs
Spec Levofloxacin
Targofloxin
Teraquin
Tian Fu Xin
Voxin
VOXIN 500MG TABLET 1 strip(s) (5 tablets each)		$1.55	Panacea Biotec Ltd
Voxin 250mg FILCOTAB / 5		$0.71
Voxin 500 mg x 2 x 10's		$32.56
evaquin
EVAQUIN tab 7.5 mg x 10's		$0.46	Captab
Evaquin 7.5mg TAB / 10x20		$5.57
EVAQUIN tab 15 mg x 10's		$0.73	Captab
Evaquin 15mg TAB / 10x20		$10.64
levofloxacin (injection)
0 .5%	100	$1.00	USA
250 mg	30	$24.25	Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
250 mg	50	$21.99	Canada, Mauritius, Singapore, Turkey, UK, USA
250 mg	100	$60.80	Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
250 mg	100	$71.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
250 mg	100	$89.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
250 mg	100	$96.00	Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
25 mg/ml	100	$116.76	USA
500 mg	10	$20.00	Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
500 mg	20	$75.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
500 mg	100	$75.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
500 mg	100	$78.00	Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
500 mg	100	$118.00	Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA
500 mg	100	$129.00	Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK
750 mg	20	$34.99	Canada, Mauritius, Singapore, Turkey, UK, USA
750 mg	50	$159.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
750 mg	60	$47.80	Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
750 mg	100	$2.00	USA
750 mg	100	$230.90	Barbados, Canada, NZ, UK
750 mg	100	$315.00	Australia, Canada, India, NZ, Turkey, Singapore, UK, USA
750 mg	100	$796.25	Canada, UK
Quixin 0.5% Solution		$11.40
Levaquin 750 mg leva-pak tablet		$27.51
levofloxacin 500 MG per 20 ML Injection
levofloxacin 750 MG in 30 ML Injection

References

Dailymed."Levofloxacin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"Levofloxacin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"Levofloxacin". http://www.drugbank.ca/drugs/DB0113... (accessed August 28, 2018).

Levofloxacino Combino - Frequently asked Questions

Can Levofloxacino Combino be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Levofloxacino Combino?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Levofloxacino Combino at the same time each day with a full glass of water (8 ounces). Drink several extra glasses of fluid each day while you are taking Levofloxacino Combino. You may take Levofloxacino Combino tablets with or without food.

Take Levofloxacino Combino oral solution (liquid) on an empty stomach 1 hour before or 2 hours after meals. Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Levofloxacino Combino will not treat a viral infection such as the common cold or flu.

This medication can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking Levofloxacino Combino.

Do not share this medication with another person (especially a child), even if they have the same symptoms you have.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What other drugs will affect Levofloxacino Combino?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Levofloxacino Combino, especially:

a diuretic or "water pill";
theophylline;
heart rhythm medication--amiodarone, disopyramide, dofetilide, dronedarone, procainamide, quinidine, sotalol, and others;
medicine to treat depression or mental illness--amitriptylline, clomipramine, desipramine, iloperidone, imipramine, nortriptyline, and others; or
NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may interact with Levofloxacino Combino, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Who should not take Levofloxacino Combino?

You should not use this medication if you are allergic to Levofloxacino Combino or other fluoroquinolones.

You may not be able to use Levofloxacino Combino if you have a muscle disorder. Tell your doctor if you have a history of myasthenia gravis.

To make sure Levofloxacino Combino is safe for you, tell your doctor if you have:

a heart rhythm disorder, especially if you take medication to treat it;
a personal or family history of Long QT syndrome;
tendon problems, arthritis or other joint problems (especially in children);
a muscle or nerve disorder;
bone problems;
liver or kidney disease;
seizures or epilepsy;
a history of head injury or brain tumor;
a history of allergic reaction to an antibiotic;
diabetes (especially if you use insulin or take oral diabetes medication);
low levels of potassium in your blood (hypokalemia); or
if you use a blood thinner (warfarin, Coumadin) and have "INR" or prothrombin time tests.

Levofloxacino Combino may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking Levofloxacino Combino. Tendon problems may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant.

FDA pregnancy category C. It is not known whether Levofloxacino Combino will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether Levofloxacino Combino passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Can Levofloxacino Combino be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Levofloxacino Combino be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Levofloxacino Combino, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Levofloxacino Combino. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.