Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet

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• Read drug prescription
• What is Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet
• Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet side effects
• Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet dosing
• Select the most affordable brand or generic drug
• Frequently asked Questions
• Who should not take Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?
• How should I take Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?
• What other drugs will affect Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?
• Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet reviews

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What is Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet

Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet works by blocking certain enzymes in the body that affect blood cell production.
Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet is used to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that affect your body's ability to produce blood cells.
Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet may also be used for purposes not listed in Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet guide.

Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may be similar to the symptoms of myelofibrosis. Call your doctor at once if you have a serious side effect such as:

• pain or burning when you urinate;
• nausea, vomiting, weakness;
• blisters or painful skin rash;
• changes in the size, shape, or color of a mole or skin lesion;
• low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
• low platelets--easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; or
• low white blood cell counts--fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing.

Common side effects may include:

• anemia;
• low platelets (easy bruising);
• dizziness; or
• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet dosing

Usual Adult Dose for Myeloproliferative Disorders:

Initial Dose:
-Platelets greater than 200 x 10/L: 20 mg orally twice a day
-Platelets 100 to 200 x 10(9)/L: 15 mg orally twice a day
-Platelets 50 to less than 100 x 10(9)/L: 5 mg orally twice a day
Maximum dose:
-Starting platelets 100 x 10(9)/L or greater: 25 mg twice a day
-Starting platelets 50 to less than 100 x 10(9)/L: 10 mg twice a day
Duration of therapy: 6 months if no spleen reduction or symptom improvement
Comments:
-Doses may be titrated based on safety and efficacy.
-If efficacy is considered insufficient and platelet and neutrophil counts are adequate, doses may be increased by a maximum of 5 mg twice daily.
-The starting dose should not be increased within the first four weeks of treatment and thereafter no more frequently than at 2 week intervals.
Uses: Intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis

Active ingredients: ruxolitinib

Select the most affordable brand or generic drug

Strength	Quantity	Price, USD	Country
Jakafi
15 mg	60	$8.00	Israel
20 mg	60	$8.00	Israel
25 mg	60	$7.00	USA
5 mg	60	$4.00	Israel
Jakafi 20 MG Oral Tablet
Jakavi
15 mg	60	$6.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg	60	$7.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
5 mg	60	$6.00	Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
Jakavi 20mg Tablet		$59.52	Novartis India Ltd
ruxolitinib
15 mg	60	$8.00	Israel
20 mg	60	$8.00	Israel
5 mg	60	$4.00	Israel
60 mg	1 vial	$2.00	Israel
60 mg	6 vial	$17.00	Israel
ruxolitinib (as ruxolitinib phosphate) 15 MG Oral Tablet
15 mg	60	$8.00	Israel
20 mg	60	$8.00	Israel
5 mg	60	$4.00	Israel
60 mg	1 vial	$2.00	Israel
60 mg	6 vial	$17.00	Israel
ruxolitinib (as ruxolitinib phosphate) 5 MG Oral Tablet
15 mg	60	$8.00	Israel
20 mg	60	$8.00	Israel
5 mg	60	$4.00	Israel
60 mg	1 vial	$2.00	Israel
60 mg	6 vial	$17.00	Israel
ruxolitinib 15 MG Oral Tablet
ruxolitinib 20 MG Oral Tablet [Jakafi]
ruxolitinib 5 MG Oral Tablet

References

1. Dailymed."Jakafi (ruxolitinib) tablet [incyte corporation]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
2. "Ruxolitinib". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
3. "Ruxolitinib". http://www.drugbank.ca/drugs/DB0887... (accessed August 28, 2018).

Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet - Frequently asked Questions

Can Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?

You should not use Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet if you are allergic to it.

Tell your doctor if you have ever had tuberculosis, if anyone in your household has tuberculosis, or if you have recently traveled to an area where tuberculosis is common.

To make sure Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet is safe for you, tell your doctor if you have:

• any type of infection;

• kidney disease (or if you are on dialysis);

• liver disease; or

• a history of skin cancer.

Using Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet may increase your risk of developing skin cancer. Talk to your doctor about this risk and what skin symptoms to watch for.

FDA pregnancy category C. It is not known whether Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet.

How should I take Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet with or without food.

The Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet tablet can also be given through a nasogastric (NG) feeding tube as follows:

• Place the tablet into 40 milliliters of water, stirring occasionally for 10 minutes.

• When the tablet is completely dispersed, place the mixture into a syringe attached to the NG tube.

• Push the plunger down to empty the syringe into the tube. Then flush the tube with 75 milliliters of water to wash the contents down.

• You must give the mixture within 6 hours after placing the tablet into the water.

To be sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. This will help your doctor determine the best dose for you to use. When you first start taking Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet, your blood will need to be tested every 2 to 4 weeks. Do not miss any follow-up visits to your doctor.

You should not stop using Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat.

What other drugs will affect Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet, especially:

• an antibiotic;

• antifungal medicine; or

• antiviral medicine to treat HIV or AIDS.

This list is not complete. Other drugs may interact with Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Can Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Jakafi (as ruxolitinib phosphate) 10 MG Oral Tablet. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology